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In pediatric patients open abdomen (OA) is applied with many and not standardized indications. Several studies have been published regarding the OA management in adults and fewer in pediatrics. Several issues are still unclear and need more high quality data. The World Society of Emergency Surgery (WSES) promoted the International Register of Open Abdomen (IROA) dedicated to adults and pediatric patients. The register is held on a web platform (Clinical Registers®) through a dedicated web site: www.clinicalregisters.org. (ClinicalTrials. gov Identifier: NCT02382770).